CM – Alex Oxlade-Chamberlain
Another fitness concern, although there is more chance of Oxlade-Chamberlain playing against his former club than the likes of Gibbs and Monreal.
CM – Aaron Ramsey
Partnering the England international in central midfield is Ramsey who is yet to show the same form that earned him so many plaudits last campaign.
RM – Alexis Sanchez
The team seem to look towards this £35m summer signing for inspiration and up against a tough side under Ronald Koeman the Chile international will need to be at the top of his game.
CAM – Santi Cazorla
With Mesut Ozil out injured this Spaniard is back in his preferred role as a No.10 and has shown in recent games that he could recapture the form that endeared him so much to the fans when he first arrived in 2012.
LM – Danny Welbeck
Although Welbeck left Manchester United because he was being played out of position too much, with so many injuries the 24-year-old is likely to be tasked with a wide role.